Micronuclei Assay of Exfoliated Oral Mucosal Cells: a Review
نویسندگان
چکیده
1. Post Graduate Student, Department of Oral Pathology and Microbiology, Teerthanker Mahaveer Dental College & Research Centre, Moradabad. 2. Reader, Department of Oral Pathology and Microbiology, Teerthanker Mahaveer Dental College & Research Centre, Moradabad 3. Senior Lecturer, Department of Oral Pathology and Microbiology, Teerthanker Mahaveer Dental College & Research Centre, Moradabad 4. Senior Lecturer Department of Oral Pathology and Microbiology, Teerthanker Mahaveer Dental College & Research Centre, Moradabad
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Micronucleus Assay of Buccal Mucosa Cells in Waterpipe (Hookah) Smokers: A Cytologic Study
Background & Objective: Micronucleus assay of buccal mucosa cells is a simple bio- monitoring method for diagnosing the genetic damages of toxic agents. The aim was to study the genotox...
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Oral cancer is most common cancer in males and third most common in females, the main causative agent being use of chewing betel quid (BQ). The micronucleus (MN) assay in exfoliated buccal cells is a useful and minimally invasive method for monitoring genetic damage in humans. Micronuclei (MN) have been proposed as good biomarker to assess cytogenetic damage. MN formation has been observed in c...
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Analysis of exfoliated buccal cell micronuclei (MN) is a sensitive method of monitoring genetic damage in the human population. In the present study 50 patients with precancerous or malignant oral epithelial lesions from the Departments of Facio-maxillary and ENT Surgery of RKMSP Hospital, Kolkata were compared with 50 age and sex matched healthy controls without any oral lesions.The MN frequen...
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OBJECTIVE Radiography is one of the most valuable diagnostic tools used in comprehensive dental care. Although there is no safe level of radiation exposure, the possible risk associated with exposure to radiation, must be elucidated. To date, a variety of assays have been proposed to assess the mutagenic potential of genotoxicants; however, these methods are typically laborious and time consumi...
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